Research Use Only: These products are sold for research use only, and are prohibited by law for human or animal consumption.
GLP-1 analog evaluated in receptor-binding and cellular signaling research.
For research use only.
Price range: $149.00 through $447.00
Peptides will arrive in a lyophilized (powder) form for maximum stability
Semaglutide is a synthetic peptide analog of glucagon-like peptide-1 (GLP-1), studied for its ability to activate GLP-1 receptors and influence metabolic signaling pathways. Research explores its effects on glucose regulation, appetite signaling, insulin response, and endocrine communication within controlled laboratory environments and cellular research models.[1]
Scientific interest in GLP-1 began in the 1980s when researchers identified its role in glucose homeostasis and hormone-mediated metabolic signaling. Early GLP-1 receptor agonists provided foundational insight but were limited by short biological duration. Semaglutide was later developed with targeted structural modifications designed to enhance peptide stability, receptor affinity, and duration of action. This advancement allowed researchers to further investigate long-acting incretin signaling and metabolic pathway regulation in experimental research settings.[2]
Sequence: HXEGTFTSDVSSYLEGQAAK-OH steric diacid-EFIAWLVRGRG
Molecular Formula: C₁₈₇H₂₉₁N₄₅O₅₉
Molecular Weight: 4113.6 g/mol
CAS Number: 910463-68-2
PubChem CID: 56843331
Synonyms: Semaglutide, NN9535, OG217SC, NNC 0113-021, GLP-1 receptor agonist (GLP-1RA), long-acting GLP-1 analog
Source: PubChem
Semaglutide has been investigated across metabolic, endocrine, and cardiovascular research disciplines. Published studies highlight its role in:
1. Glucose & Insulin Signaling
Laboratory models evaluate its influence on glucose metabolism, insulin pathways, and endocrine regulatory systems.[1]
2. Appetite & Energy Balance
Research explores how GLP-1 receptor activation may affect signaling associated with satiety and nutrient regulation.[3]
3. Lipid & Cardiovascular Physiology
Studies assess potential effects on cholesterol processing, lipid pathways, and systemic cardiometabolic signaling.[1,3]
4. Structural & Molecular Stability
Scientific investigations examine how peptide modifications support extended receptor engagement and metabolic research utility.[2]
By functioning as a long-acting GLP-1 receptor agonist, Semaglutide provides researchers with a platform to examine incretin biology, endocrine communication, metabolic regulation, and peptide-receptor interaction mechanisms. Its structural design supports extended receptor activity, making it valuable in research focused on glucose metabolism, hormonal regulation, and systemic metabolic pathways.
Ongoing studies continue to expand understanding of Semaglutide’s biochemical behavior and research applicability.[1–3]
Peptides are short chains of amino acids that occur naturally in organisms, where they act as messengers in many biological systems. While some peptides have been developed for medical use, laboratory research focuses on understanding their activity at the cellular level, examining how they impact essential processes in vitro.
Products from LabGrade Peptides are for in vitro research only. Please conduct your own research before working with these compounds. After purchasing, a team member will reach out via text for general support.
Orders are typically processed and shipped within 24 hours on weekdays. Delivery times vary by location, but most domestic orders arrive within 3–5 business days. You’ll receive tracking information as soon as your order ships.
Peptides are supplied as lyophilized powder. They do not come reconstituted, and any extra supplies must be sourced separately for research applications.
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